$ 43.99

RestorFloraTM is a special-purpose combination probiotic containing the friendly yeast species Saccharomyces boulardii. S. boulardii is used for advanced support of a healthy intestinal environment when diarrhea, antibiotic-associated diarrhea, C. difficile-associated diarrhea and gastrointestinal upset are a special concern*.

RestorFlora is the only pharmaceutical-strength, 3-strain probiotic that can survive the harsh stomach environment and arrive in the gut at full strength. RestorFlora is best used in combination with a general purpose probiotic, such as MegaSporeBiotic.


Size: 50 capsules

RestorFlora is the first therapeutic probiotic product that combined three well studied and widely used probiotic strains: Saccharomyces boulardii, Bacillus subtilis HU58 and Bacillus clausii.

Several clinical studies show that the friendly yeast S. boulardii (also called Sac. B) is helpful for support with gut disorders1, especially gut bacterial challenges, antibiotic-associated diarrhea and C. difficile associated diarrhea2 *. The unique properties of S. boulardii make it a beneficial addition to a probiotic regimen when extra support is needed for difficult gastrointestinal challenges.

Dual action support is achieved by the addition of B. subtilis HU58 and B. clausii, which help support immune system function and the reduction of GI inflammation.*

RestorFlora requires no refrigeration, making it easy to store, ship, and travel with. The product is made in a GMP facility to ensure maximum quality, potency and batch-to-batch consistency. We offer this physician’s-strength probiotic at the lowest pricing allowed by the manufacturer.

Product Questions? Please see our RestorFlora FAQ page for answers to common questions about this product.


  1. Bacteria and yeasts in the treatment of acute and chronic infectious diarrhea. Part II: Yeasts. Vandenplas Y, July 1999, Clin. Microbiol. Infect. 5 (7): 389–395
  2. Role of probiotics in antibiotic-associated diarrhea, Clostridium difficile-associated diarrhea, and recurrent Clostridium difficile-associated diarrhea. Surawicz CM, July 2018, J Clin Gastroenterol. 42 (Suppl 2): S64–70

* FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.


RestorFlora is a potent, special-purpose product meant for temporary use during active gut challenges. It is best used in combination with MegaSporeBiotic and not as a “stand-alone” probiotic.

For first time users, we HIGHLY recommend starting with less than the suggested amount listed on the bottle. Start slowly to help avoid any GI discomfort. Take with food or right after a meal.



PLEASE follow the Probiotic Restoration Guide carefully
to reduce the risk of gut discomfort:

Click here to open the Probiotic Restoration Guide


If you experience any discomfort (abdominal cramping or loose stools due to changes in gut bacteria), temporarily decreasing the amount you take should eliminate uncomfortable symptoms. Download the Probiotic Restoration Guide above for complete details.


RestorFlora is generally well tolerated by most people.

Do not take RestorFlora if:

  • You have a known allergy to yeast (like Saccharomyces cerevisiae)
  • You have an indwelling vascular catheter, a peripherally inserted central catheter (PICC line) or a central venous catheters (CVC).

RestorFlora has not been specifically studied for safety during pregnancy or for nursing mothers. Be sure to consult with your doctor before using during pregnancy or nursing.

Be sure to follow the Probiotic Restoration Guide above and start with less than the amount on the label, especially if you’re a first time user. Increase usage amount gradually over 3 weeks up to the full amount, or according to your tolerance. If adverse symptoms occur, then reduce usage amount or stop taking the product until symptoms clear, then start again slowly, if well tolerated.

Please consult with your doctor before starting any nutritional supplement program or before using this or any product during pregnancy, or if you have a serious medical condition.


Per Capsule:

  • Saccharomyces boulardii, 5 billion CFU
  • Bacillus subtilis, HU58™, 1 billion CFU
  • Bacillus clausii, 1 billion CFU
  • Other Ingredients: Pharmaceutical grade cellulose, vegetable capsule (cellulose and water).
  • No binders, fillers or flow agents added.
  • Contains NO dairy, wheat, gluten, corn, rice, salt, sugar, soy, artificial colors or flavors.
  • GMO free.


Microbiome Labs was originally established as Physicians Exclusive in 2013 as an organization focused on providing probiotic bacteriotherapy. Their goal is to provide integrative solutions and clinical research data to address indications that stem from digestive and immune health issues. Probiotic products are made in a GMP facility to ensure potency, quality and consistency.

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