


About Microbiome Labs
Microbiome Labs was founded by microbiologist Kiran Krishnan and Dr. Tom Bayne, driven by a simple frustration: too many supplements make claims with little research behind them. That mission led to the discovery of spore-based Bacillus strains stable enough to survive digestion — the foundation of MegaSporeBiotic. The company has since pioneered spore-based probiotics and, with the backing of Novonesis, a global biotech leader, continues to invest heavily in clinical research to support its formulas. It’s why we’ve trusted and recommended their products since 2017.
References
1. Ramezani Kapourchali F, Glueck B, Han Y. A Spore-Forming Probiotic Supplement Improves the Intestinal Immune Response and Protects the Intestinal Health During Recurrent Clostridioides difficile Colonization in Mice. JPEN J Parenter Enteral Nutr. 2020 Nov;44(8):1428-1438.
2. Szajewska H, Kołodziej M. Systematic review with meta-analysis: Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea. Aliment Pharmacol Ther. 2015;42(7):793-801.
3. Kotowska M, Albrecht P, Szajewska H. Saccharomyces boulardii in the prevention of antibiotic-associated diarrhea in children: a randomized double-blind placebo-controlled trial. Aliment Pharmacol Ther. 2005;21(5):583-590.
4. Pothoulakis C, Kelly CP, Joshi MA, et al. Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. Gastroenterology. 1993;104(4):1108-1115.
5. Mehta DS, de Souza A, Jadhav SS, Devale M. A Study of Probiotic Bacillus subtilis HU58 for the Management of Antibiotic-Associated Diarrhoea in Adults. The Indian Practitioner. 2020;73(4):22-28.
6. Sorensen K, Jog P, Mankar S, Holz C, Jadhav S. Effects of spore-forming probiotic Bacillus subtilis HU58™ in children with antibiotic-associated diarrhoea: a randomised, double-blind, placebo-controlled trial. Benef Microbes. 2025/2026;17(1). DOI: 10.1163/18762891-bja00086
7. Surawicz CM. Role of probiotics in antibiotic-associated diarrhea, Clostridium difficile-associated diarrhea, and recurrent Clostridium difficile-associated diarrhea. J Clin Gastroenterol. 2008;42(Suppl 2):S64-70.
Why Choose Embrace Health Naturals?
- Professional grade supplements backed by clinical research.*
- Product support and guidance with all purchases.
- Family-owned since 2008 and led by a microbiologist – trusted by thousands of satisfied customers.
- Winner of the 2024 Microbiome Pioneers award from Microbiome Labs.
- No artificial colors or flavors, gluten, GMOs, cheap fillers, or low-quality additives.
- All of our products are tested for potency, purity and safety.



















