$ 45.99

PyloGuard™ contains a special strain of postbiotic (non-living) bacteria, Lactobacillus reuteri DSM17648, to support binding and excretion of H. pylori (Helicobacter pylori) species in the gut.

Postbiotics contain cell fragments of probiotic organisms that provide specific benefits inside the gut without any of the potential downsides of ingesting the live organisms. The dead cell fragments of the Lactobacillus reuteri DSM17648 attach to and bind the H. pylori bacteria. The bound H. pylori can then be eliminated through the digestive tract.

Using the mechanism of postbiotics supports the gut microbiome instead of disrupting or destroying it. It can be used as the first line of defense before the use of indiscriminate antibiotics and other microbe-killers that can disrupt the microbiome, leading digestive problems and other health issues.

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Size: 30 capsules

PyloGuard™ is a dietary supplement designed to support the body’s natural processes for elimination. It contains patented Lactobacillus reuteri DSM17648, which can attract specific organisms in the intestine and support their removal via the digestive tract. This particular strain of L. reuteri specifically binds to H. pylori in the stomach and supports overall digestive health*.

The Helicobacter pylori (H. pylori) bacterium is native to the human gut, but overgrowth of this species can lead to chronic health challenges. Estimates say that up to 50% of the world’s population carries H. pylori in their GI tracts. H. pylori is spread through direct contact with people or household pets through saliva, feces, or contaminated food or water.

PyloGuard™ is a postbiotic containing only inactivated organisms that don’t disrupt commensal gut flora. This revolutionary postbiotic works WITH the microbiome instead of against it, supporting the fight against H. pylori while maintaining gut microbial balance. Containing only inactivated organisms, PyloGuard™ is safe for those with immune issues that might prevent them from taking live probiotics*.

* FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.


Ages 9+: Open 1 capsule into 8 oz of water and drink once daily on an empty stomach. Children under the age of 9, please consult your healthcare practitioner*.

Special closeout: best if used by February 2024.

* FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.


Note: Most people tolerate PyloGuard™ well. But if you are especially sensitive to supplements or diet changes, then starting more slowly than usual may be helpful. If adverse symptoms occur, then reduce usage amount or stop taking the product until symptoms clear, then start again slowly, if well tolerated.

Please consult with your doctor before starting any nutritional supplement program or before using this or any product during pregnancy, or if you take medications or have a medical condition.


Per 1 Capsule:

  • Limosilactobacillus reuteri DSM 17648 – 200 mg (20 Billion Cells)
  • Other Ingredients: Nutriose® (corn dextrin), Natural Flavors, Vegetarian Capsule (Cellulose, Water, Acacia Fiber.
  • Contains NO dairy, wheat, gluten, soy, eggs, nuts or artificial colors.


Microbiome Labs was originally established as Physicians Exclusive in 2013 as an organization focused on providing probiotic bacteriotherapy. Their goal is to provide integrative solutions and clinical research data to address indications that stem from digestive and immune health issues. Probiotic products are made in a GMP facility to ensure potency, quality and consistency.

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