MegaSporeBiotic Two Pack

$ 119.98

Not all probiotics are created equal. MegaSporeBioticTM is a pharmaceutical-strength, 5-strain all-spore probiotic that can survive the harsh stomach environment and arrive in the gut at full strength. MegaSporebiotic is the most effective and most potent spore-based product available.

MegaSporeBiotic supports digestive and immune function.* It supports the growth of natural lactobacillus species and helps control non-favorable bacterial overgrowth.* It’s also the first carotenoid rich probiotic available to the market that actually produces multiple antioxidants on site within the digestive tract.

9 Reasons to Choose MegaSporeBiotic

You get FREE U.S. Shipping with this pack.

Available in 60 or 180 count size bottles.


Size: 60 capsules each

Because MegaSporeBiotic is made from soil based spore-forming organisms, they reach the digestive tract in full potency. Studies have shown that leading probiotic formulas containing Lactobacillus and Bifidobacteria are drastically reduced or completely killed by heat and stomach acids.

Contains five well researched strains of soil-based organisms that create favorable conditions to promote the growth of your resident “good” bacteria, like Lactobacillus and Bifidobacteria species.

MegaSporeBiotic requires no refrigeration, which is ideal for shipping and convenient while traveling. The product is made in a GMP facility to ensure maximum quality, potency and batch-to-batch consistency. We offer this physician’s-strength probiotic at the lowest pricing allowed by the manufacturer.

NOTE: If severe diarrhea or antibiotic-associated diarrhea is a concern, combine our S. boulardii probiotic along with MegaSporeBiotic.

Product Questions? Please see our MegaSporeBiotic FAQ page for answers to common questions about this product.

* FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.


MegaSporeBiotic is very potent. For first time users, we HIGHLY recommend starting with less than the suggested amount listed on the bottle. Start slowly to help avoid any GI discomfort. Take with food or right after a meal.



PLEASE follow the Safe Use Guide carefully
to reduce the risk of gut discomfort:

Click here to open the Safe Use Guide


If you experience any discomfort (abdominal cramping or loose stools due to changes in gut bacteria), temporarily decreasing the amount you take should eliminate uncomfortable symptoms. Download the Safe Use Guide above for complete details.


MegaSporeBiotic is generally well tolerated by most people. Be sure to follow the Safe Use Guide above and start with less than the amount on the label, especially if you’re a first time user. Increase usage amount gradually over 3 weeks up to the full amount, or according to your tolerance. If adverse symptoms occur, then reduce usage amount or stop taking the product until symptoms clear, then start again slowly, if well tolerated.

Please consult with your doctor before starting any nutritional supplement program or before using this or any product during pregnancy, or if you have a serious medical condition.


Per 2 Capsules:

  • 4 Billion spore cells, 350 mg
  • Bacillus indicus, HU36™
  • Bacillus subtilis, HU58 ™
  • Bacillus coagulans
  • Bacillus licheniformis
  • Bacillus clausii
  • Other Ingredients: Hypo-allergenic plant fiber prebiotic (cellulose), vegetable capsule.
  • No binders, fillers or flow agents added.
  • Contains NO dairy, wheat, gluten, salt, sugar, soy, artificial colors or flavors.
  • GMO free.


About Microbiome Labs Products

Microbiome Labs was originally established as Physicians Exclusive in 2013 as an organization focused on providing probiotic bacteriotherapy. Their goal is to provide integrative solutions and clinical research data to address indications that stem from digestive and immune health issues. Probiotic products are made in a GMP facility to ensure potency, quality and consistency.

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